Wellbutrin, manufactured by GlaxoSmithKline, is an antidepressant later marketed as the smoking cessation drug Zyban. Wellbutrin has been linked to serious side effects, such as depression, violent mood swings, suicidal thoughts, and seizures. In 2004, the FDA required a black box warning to be placed on Wellbutrin's packaging, which advises: "Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents with MDD and other psychiatric disorders." Family and friends who witness any of the above behaviors in people taking Wellbutrin should advise the person to stop taking the drug and consult a physician immediately.